The uptake and elimination of halothane in dogs: a two- or multicompartment system? I: Gas chromatographic determination of halothane in blood and in inspired and end-tidal gases.
نویسندگان
چکیده
The gas chromatographic determination of volatile organic anaesthetic agents in blood and in respiratory gases is described. The analysis in blood is based on a head space technique. Sampling of inspired and end-tidal gases is carried out by means of a system including a gas sampling valve.
منابع مشابه
The uptake and elimination of halothane in dogs: A two or multicompartment system? II: Evaluation of wash-in and wash-out curves.
In 14 mongrel dogs wash-in and wash-out curves for halothane were obtained from measurements of arterial blood, mixed venous blood and end-tidal gas. From a certain point in the wash-in period the halothane concentration of arterial blood can be calculated from the halothane concentration in end-tidal gas and the blood-gas partition coefficient for halothane. Analysis of the curves shows that t...
متن کاملAnaesthetic uptake and elimination: is there a difference between halothane and isoflurane in the dog?
In two groups of dogs, the uptake and elimination of halothane and isoflurane were studied using a closed-loop anaesthetic system which automatically controlled end-tidal halothane and isoflurane partial pressures at equi-MAC concentrations. Haemodynamic and respiratory variables were recorded and the anaesthetic partial pressures were measured in the inspired and expired air, as well as in the...
متن کاملمقایسه روش های اینداکشن استنشاقی Single breath inhalation و Tidal volume technique با اینداکشن وریدی (نسدونال، ساکسینیل)، دانشگاه علوم پزشکی تهران، 1379
The induction characteristic of halothane in nitrous oxide and oxygen were compared with halothane in oxygen alone and intravenous induction with thiopentum and succinylcholine.Materials and Methods: A vital capacity technique was used for the gaseous induction groups using a mapleson F system and a 1-litre reservoir bag. four end points of anesthesia were recorded: time to cessation of hand gr...
متن کاملDetermination of the partial pressure of halothane (or isoflurane) in blood.
A gas chromatographic method is described for the direct quantitative determination of the partial pressure of halothane (or isoflurane) in blood as well as the blood-gas partition coefficient. A head space technique and a flame ionization detector were used. Standard blood was obtained by equilibrating patients' blood with known gas concentrations in a tonometer. Using an infra-red analyser to...
متن کاملA comparison between the effect of halothane and propofol on liver enzymes after general anesthesia
Background: Halothane is the routine used inhalation anesthetic drug in the world but at present, there is an increasing interest for using intravenous anesthetics like propofol. The purpose of this study was to compare these anesthetic effects on hepatic enzymes.Methods: From 2006 to 2007, this study was performed on fifty eight patients classified in class I of American Society of Anesthetics...
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ورودعنوان ژورنال:
- British journal of anaesthesia
دوره 47 10 شماره
صفحات -
تاریخ انتشار 1975